Sentinel Lymph node biopsy in Melanoma
Clinical Significance of Sentinel Lymph node in melanoma:
SLNB is very accurate in predicting the status of the remaining regional
lymph nodes.It is currently the most significant independent prognostic indicator for survival when compared with all other factors, including tumour thickness and the presence of ulceration. According to recent studies,the relapse rate for H&E detected SLN positive patients is higher (up to67%), whereas the relapse rate for SLN negative patients is low (2–6%) during the same period.
For details about the pathology protocols for sentinel Lymph node
handling,how to avoid false positive and false negative results and more
details, please visit www.oncopathology.blogspot.com
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