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Significance of Atypical Small Ascinar Proliferation (ASAP) in Prostate needle biopsy

Many time while reporting prostate needle biopsy, we come across features, which are suspicious for malignancy, but hinder a definitive diagnosis of carcinoma, because of concern about over diagnosis. These are the cases, which are labelled as ASAP–atypical small acinar proliferation.

Diagnostic criteria for ASAP and its clinical significance is discussed at www.oncopathology.blogspot.com

Hello,
Some more information:
High grade PIN with adjacent small atypical glands (PINATYP)

May be difficult to determine if small glands represent budding / tangentially sectioned glands from high-grade PIN or invasive cancer next to high grade PIN; no reliable differentiating features

Risk of cancer on repeat biopsy was 46%, higher than high grade PIN alone, indicating patients should be rebiopsied.