Dysplasia in inflammatory bowel disease
The pathologic reporting of endoscopic biopsy specimens with inflammatory bowel disease must convey an assessment of the disease activity and distribution.
In addition, the pathologist must render an opinion on the presence or
absence of dysplasia.
Agreeing on the terminology is relatively easy. Agreeing on the morphologic presence or absence of dysplasia is another issue. Studies have shown poor interobserver reproducibility with regard to recognizing and diagnosing dysplasia. Low grade dysplasia (LGD), as one might guess, suffers from the worst interobserver variability.
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