Confident diagnosis on small biospy specimen.
Many times the distinction of non-neoplastic lymphoid follicles vs.
neoplastic lymphoid follicles can be readily made on standard H&E
morphology alone.
As we all know however, we see cases where this distinction is
challenging, and in other situations we are faced with minuscule or
suboptimal material.
By understanding the expected phenotype of the lymphoid cells within
each of the various types of lymphoid follicles, one can frequently
render a confident diagnosis, even in the face of suboptimal material or
a minimal biopsy sample.
Please visit www.oncopathology.blogspot.com for more details.
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