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I recently did a brain autopsy on a 70-year-old woman who died from an intraparenchymal brain hemorrhage after a seven-year history of progressive dementia. The gross photograph follows: I know what you’re thinking: an amyloid angiopathic bleed, or perhaps a hypertensive bleed, in a patient with Alzheimer disease. That’s what I was thinking until I [...]
The College of American Pathologists (CAP) unveiled today new resources and features on MyBiopsy.org to help patients better understand their disease. Neuropathological diagnoses discussed on the site include: anaplastic astrocytoma, glioblastoma, pilocytic astrocytoma, and oligodendroglioma. If one of your patients has questions about one of these pathological diagnoses, you can refer them to this website, [...]
Two neuropathologists are prominently spotlighted in an article by Malcolm Gladwell in the October 19 issue of The New Yorker. The article explores a provocative question raised by autopsy results on football players: namely, should football be illegal? Featured are Dr. Ann McKee (pictured), neuropathologist at the Veterans Hospital in Bedford, Massachusetts and Dr. Bennet [...]
If you consider yourself a blue-collar neuropathologist, a nice resource has appeared on the web for you. Henry Stewart Publications, based in London, is providing free access to a wide variety of on-line biomedical lectures in the form of the Henry Stewart Talks. Many different biomedical topics are addressed, but one series focuses on neurodegenerative [...]
In the the current issue of Archives of Pathology and Laboratory Medicine, a team including Bette K. Kleinschmidt-DeMasters, MD authored an interesting article entitled Rare Nerve Lesions of Non-Nerve Sheath Origin: a 17-year Retrospective Series. DeMasters, neuropathology chief at the University of Colorado in Denver, and her team did a computer search of all peripheral [...]
A common theme among neurodegenerative diseases is that there is a some kind of “nucleating protein” which aggregates within specific areas of the brain. There is debate as to whether the aggregates cause disease, or are simply an attempt by brain cells to sequester bad proteins. If the former is true, then therapy should be [...]
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