pathtalk.org is a weblog about pathology and laboratory medicine.

Active Discussions Pathology Blogs Medical Blogs Affiliates

About Brian Moore

No biographical information is available for this author.
Contact Brian Moore:
E-mail | Website

Posts by Brian Moore

Posted by
Brian Moore

Date
May 26, 2009
2:14 pm

Tagged
,

Category
Cases, Neuropathology

A 75-year-old man with a large, subretinal mass requiring enucleation

The patient is a 75-year-old male who reported to his ophthalmologist complaining of failing vision as well as intermittent “flashes of light” in his left eye over the previous four months. Examination of the left eye revealed markedly elevated intraocular pressure. Fundiscopic examination revealed a large grayish brown subretinal mass with surrounding retinal folds in [...]

Posted by
Brian Moore

Date
May 14, 2009
5:35 pm

Tagged

Category
General

A child presenting with lack of coordination and a basal ganglia lesion

An 8-year-old girl presented with lack of coordination of the right arm and leg progressing over the course of six months. Occasionally, the girl would hold her right arm in a postured decorticate position when she would run; and she would suffer frequent falls when playing. Physical examination showed right-sided hemidystonia and rigidity. An MRI [...]

Posted by
Brian Moore

Date
May 8, 2009
10:28 am

Tagged
, ,

Category
General

D.T. Max writes the behind-the-scene history of prion disease

Most of us accept the party line that there are three basic forms of Creutzfeldt-Jakob disease (CJD): acquired, inherited, and sporadic. The general neurology and neuropathology textbooks do not acknowledge that the very existence of sporadic CJD is controversial. But D.T. Max (picture from nytimes.com), in his book The Family That Couldn’t Sleep: A Medical [...]

Posted by
Brian Moore

Date
April 23, 2009
10:25 am

Tagged

Category
General

“Refrigerator” Perry hospitalized due to complications of Guillain-Barré syndrome

According to an associated press report, the gargantuan defensive tackle William “The Refrigerator” Perry (pictured below), who helped lead the Chicago Bears to a 1985 Super Bowl victory, has been hospitalized after complications related to Guillain-Barré syndrome (GBS). Perry remains in serious condition at Aiken Regional Medical Center, located in his boyhood home of Aiken, [...]

Posted by
Brian Moore

Date
April 17, 2009
12:33 pm

Tagged
,

Category
Chemistry, General, Neuropathology

Beta-2 Transferrin: The Tau of Trauma

One of our lab techs posed a question about beta-2 transferrin testing on cerebrospinal fluid (CSF). Because beta-2 transferrin is a normal constituent of CSF, but not of plasma or mucosal secretions, it is useful in determining whether a patient’s nose or ear is leaking CSF versus some other fluid. This is important in determining [...]

Posted by
Brian Moore

Date
April 10, 2009
12:00 pm

Tagged
,

Category
Cases, Neuropathology

What is the role of “utrophin” immunofluorescent staining in muscle biopsy evaluation?

We received a muscle biopsy recently from a 5-year-old girl who was likely a dystrophin mutation carrier. Her muscle biopsy displayed a patchwork pattern of dystrophin positive and dystrophin negative muscle fibers. Utrophin was upregulated in fibers deficient for dystrophin. So, what is utrophin? It is the autosomal homologue of dystrophin. To quote the Dubowitz [...]

← Before After →

Subscribe

If you would like to subscribe to the site, you can use our RSS feeds, follow us on twitter, or join our email list.

Click here to learn how.

About

The mission of this site is to provide an interesting, engaging and informative collection of posts on a variety of pathology topics.

Click here for more.

Contact

We welcome your comments and suggestions. If you would like, you can contact us using this form.

Featured sites

Pathologypics--An interactive pathology image-sharing database.

LabSoftNews--Bruce Friedman’s pathology informatics weblog.

Monthly Archives

View All Archives

← Back to Home

© pathtalk.org || Terms of use.