About Mark Pool
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Its is my great pleasure to inform you that Oncopath Diagnostics-India’s first virtual Cancer Pathology centre has started at Pune. !!!! With the help of India’s first and Only digital pathology slide scanning system at Oncopath diagnostics, pathologists from USA, UK and Canada will be able to provide expert consultation to patients in India !!!! This centre will be specially helpful for patients and physicians/pathologists [...]
www.oncopathology.info. Atrophy looks suspicious for adenocarcinoma at first glance. the nuclei are small and hyperchromatic. No prominent nucleoli are seen. Some glands are lined by obviously benign flattened atrophic epithelium. The immunostain for high molecular weight cytokeratin can be helpful in distinguishing between atrophy (fragmented basal cell layer) from atrophic variant of prostatic adenocarcinoma (no [...]
The following pieces of tissue (labeled “skin”) were received in the laboratory from an 80 year old man. No further history was available. On closer examination, they appeared to be friable ‘scabs’:
Answer: Copepods are involved in the following parasite life cycles: 1. Diphyllobothrium latum, the broad fish tapeworm 2. Dracunculus medinensis, the Guinea worm 3. Spirometra spp., the cause of sparganosis in humans 4. the agents of gnathostomiasis: Gnathostoma spinigerum and Gnathostoma hispidum
I would hope that nearly all physicians in the course medical school, residency, fellowship and junior staff time encounter a mentor or two along the way. I have been fortunate enough to have several good mentors and a few great ones. Among those is Dr. Joe Chaffin, recently appointed medical director and vice president of [...]
The following objects are Cyclops–one of the most common genera of microscopic fresh water Copepods (small crustaceans) that are involved in a number of parasite life cycles. So the question for this week: Which human parasites have Copepods in their life cycle?
Answer, Part I: Trichinella spp. Although Trichinella spiralis is the most common species to infect humans in the United States, it is generally not possible to speciate based on morphologic features. The exception is Trichinella pseudospiralis whose larvae are not encapsulated compared to T. spiralis, T. nativa, T. nelsoni, T. britovi, and T. murrelli which [...]
There is an interesting article in this month’s Atlantic Monthly regarding the “flexible” nature of medical statistics and the way that researchers (often unknowingly) massage statistical analyses to support favored hypotheses. The article is essentially a layman’s overview of the work of John P. A. Ioannidis, whose paper “Why Most Published Research Findings Are False” [...]
The following were an incidental finding at autopsy. Shown are hematoxylin and eosin stained sections of human tongue:
Answer: Leishmania spp. amastigotes. Note the small (2-5 micron) oval-shaped objects within and outside of macrophages, with a nucleus and classic rod-shaped kinetoplast. The large purple objects are macrophage nuclei.
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