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About Prashant Jani

A Progressive pathologist with Special interest in Oncopathology.
Contact Prashant Jani:
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Posts by Prashant Jani

Posted by
Prashant Jani

Date
March 2, 2010
6:28 pm

Tagged

Category
General

High Grade Prostatic Intraepithelial Neoplasia (HGPIN)

High Grade Prostatic Intraepithelial Neoplasia (HGPIN):
Common questions asked about HGPIN are :
-How do we as pathologists make these diagnoses?
-What do they mean for the patient in terms of cancer risk?
-What is/are the optimal strategies for follow-up so that if cancer does eventually develop it is caught at an early, curable stage?
These questions are shortly discussed [...]

Posted by
Prashant Jani

Date
September 24, 2009
12:33 pm

Tagged

Category
General

Dysplasia in inflammatory bowel disease

The pathologic reporting of endoscopic biopsy specimens with inflammatory bowel disease must convey an assessment of the disease activity and distribution.
In addition, the pathologist must render an opinion on the presence or
absence of dysplasia.
Agreeing on the terminology is relatively easy. Agreeing on the morphologic presence or absence of dysplasia is another issue. Studies have shown [...]

Posted by
Prashant Jani

Date
September 16, 2009
10:18 am

Tagged

Category
General

Making Sure Your Lab Reports Are Easy to Understand

         A portion of clinical error results from the misinterpretation of laboratory data. Powsner et al reported that surgeons misunderstood 30% of pathology reports.
       Whether one communicates test results electronically, by fax, or on paper, one should periodically review the content and layout of the reports to make sure they are as useful as possible. [...]

Posted by
Prashant Jani

Date
July 3, 2009
9:43 am

Tagged

Category
General

Immunopheotype of Gastrointestinal stromal tumours (GIST)

Histogenesis:
It has been suggested that GISTs originate from the interstitial cell of Cajal (ICC), or from a primitive stem cell that differentiates towards both the ICC and smooth muscle phenotye.
Sites:
GISTs occur at every level of the GI tract. Most tumours arise in the stomach (60%) and about
20–30% occur in the small intestine. Colorectal and oesophageal [...]

Posted by
Prashant Jani

Date
June 2, 2009
2:44 pm

Tagged

Category
General

Significance of Atypical Small Ascinar Proliferation (ASAP) in Prostate needle biopsy

Many time while reporting prostate needle biopsy, we come across features, which are suspicious for malignancy, but hinder a definitive diagnosis of carcinoma, because of concern about over diagnosis. These are the cases, which are labelled as ASAP–atypical small acinar proliferation.
Diagnostic criteria for ASAP and its clinical significance is discussed at www.oncopathology.blogspot.com

Posted by
Prashant Jani

Date
May 20, 2009
9:35 am

Tagged

Category
General

Sentinel Lymph node biopsy in Melanoma

Clinical Significance of Sentinel Lymph node in melanoma:
SLNB is very accurate in predicting the status of the remaining regional
lymph nodes.It is currently the most significant independent prognostic indicator for survival when compared with all other factors, including tumour thickness and the presence of ulceration. According to recent studies,the relapse rate for H&E detected SLN positive [...]

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