Sorry for the delay in following up with my case! It was a good initial presentation of chronic myelogenous leukemia, chronic phase. So, to start off with, the 5% “unclassified cells” were myeloid blasts without Auer rods. In addition, the peripheral smear shows mostly granulocytes in varying stages of maturation. The mature bands and neutrophils [...]
Yesterday I posted a short note with reference to a story involving an ACLU lawsuit against Myriad Genetics which has re-opened the discussion about patenting genes, that is human DNA. The company of course went through this discussion to obtain the patent as others have and are no doubt prepared for this action to protect [...]
www.oncopathology.blogspot.com 1) Molecular profiling may help determine patient’s response to cancer therapies, research suggests. A pilot study of molecular profiling of tumors, helped to identify therapies that ultimately had an impact on the disease.The University of Texas MD Anderson Cancer Center and the Memorial Sloan-Kettering Cancer Center are “striving to profile individual tumors so that [...]
Warfarin is one of the most commonly prescribed anticoagulants for prophylaxis and treatment of venous and arterial thromboembolic disorders or those at high risk for such disorders. Warfarin also has an FDA-issued “Black Box” warning for a high risk of fatal bleeding, most commonly from the gastrointestinal tract and in the brain. It acts by [...]
Testing-testing: CGH me baby: I want to know how I measure up to the reference. This is a very superficial post touching on an increasingly utilized testing methodology. Comparative genomic hybridization (CGH) (also has been called “competitive”) is a method for scanning the entire genome for variations in DNA copy number which is not currently [...]
The ASCP daily newsletter dated 10/12/07 had a short paragraph about home kit DNA diagnostics. Risk assessment for tailored treatment plans is a marketing strategy supporting the use of DIY (do-it-yourself) DNA swabs fishing for SNPs (single nucleotide polymorphisms) deemed as high risk in some common diseases such as atrial fibrillation. The current prevalence of [...]
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