pathtalk.org is a weblog about pathology.

Posts from October 2007

Posted by Gretchen Galliano
30 October 2007 @ 5pm

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General

Testing-testing: drug dosing based on SNPs?

Warfarin is one of the most commonly prescribed anticoagulants for prophylaxis and treatment of venous and arterial thromboembolic disorders or those at high risk for such disorders. Warfarin also has an FDA-issued “Black Box” warning for a high risk of fatal bleeding, most commonly from the gastrointestinal tract and in the brain. It acts [...]


Posted by Kenneth Youens
29 October 2007 @ 10pm

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Cases

Giant cell pneumonia with DiGeorge syndrome

Clinical History
A 7 month-old male was admitted for severe pneumonia with respiratory compromise. Laboratory studies demonstrated leukocytosis and profound hypocalcemia. An inherited immunodeficiency syndrome was suspected. A CT scan of the chest revealed bilateral lobar pneumonia, and no thymus was seen. Dual-probe fluoresence in-situ hybridization for deletions of 10p13p14 and [...]


Posted by Gretchen Galliano
25 October 2007 @ 7pm

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General

Testing-testing: CGH me baby!!

Testing-testing: CGH me baby: I want to know how I measure up to the reference.
This is a very superficial post touching on an increasingly utilized testing methodology.
Comparative genomic hybridization (CGH) (also has been called “competitive”) is a method for scanning the entire genome for variations in DNA copy number which is not currently common in [...]


Posted by Trent McBride
24 October 2007 @ 3pm

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General

Objective Pathology

Via Keith Kaplan’s Digital Pathology Blog, I found the website for Objective Pathology, a telepathology organization “focused on enhancing and accelerating educational and diagnostic pathology workflows”. There is a lot of good stuff at their site, but my favorite is the narrated virtual slide tours - there is an example of multiple myeloma here. [...]


Posted by Trent McBride
23 October 2007 @ 11am

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Off the stage

Pre-Paid Health Care

The front page of the Wall Street Journal got a little buzz yesterday from the health care community, medical bloggers and the pathology residency program directors among them. It profiled West Virginia primary care doc Vic Wood, who has reinvented his practice by offering “prepaid” services:
For a monthly fee of $83 per individual or [...]


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