pathtalk.org is a weblog about pathology and laboratory medicine.

Posts from October 2007

Power Sign-Out

If you just like the sound of that phrase, like I do, check out Dr. Bruce Friemdan’s blog LabSoftNews where he discussed a seminar dedicated to improving surgical pathology workflow. Dr. Friedman is well known in the field of informatics and is part of the inspiration for this blog. He has put together the Lab [...]

Acute appendicitis: a surprising finding

Clinical Presentation A 14-year-old boy with no significant past medical history presented to the emergency department complaining of severe abdominal pain which had begun several hours prior in a periumbilical location, then had migrated to the right lower quadrant. Physical examination revealed marked right lower quadrant abdominal tenderness, and a complete blood count was remarkable [...]

Testing–testing: CRP–hs or unleaded?

C-Reactive Protein CRP is a lab test which can used to monitor inflammation. It is a non-organ specific acute phase response protein (acute phase response = pathophysiologic changes which accompany inflammation). It can be used in a variety of clinical settings when an inflammatory process is a concern. CRP levels can rise in acute infection, [...]

Lung Cancer Screening in the News

The National Cancer Institute has commissioned the National Lung Cancer Screening Trial, to the tune of 50,000 participants and $200 million. This huge and expensive trial comparing patients screened by CT scan with those screened by X-ray hopes to definitively answer the question of whether lung cancer screening is beneficial. The US Preventative Services Task [...]

Trouble With State Medical Examiners

Reason Magazine’s Radley Balko has an exposé (a shorter version has been published in the Wall Street Journal) on the broken medical examiner system in Mississippi, and, in particular, the troubling case of Dr. Stephen Hayne, an “entrepreneurial” pathologist who gives all forensic pathologists a bad name.   Hayne is the de facto state medical examiner for [...]

Miliary tuberculosis

Clinical History A 30-year-old Hispanic man with a history of diabetes mellitus had a staphylococcal abscess of the calf several weeks prior to presentation that was treated with antibiotics. He was in his usual state of health until two to three weeks before presentation, when he developed rapidly progressive leg pain, fever, and myalgias. He [...]

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