www.oncopathology.blogspot.com Sentinel lymph node mapping is now performed on selected patients who opt for conservative surgery to treat their breast cancer. The procedure involves the surgical identification of those axillary lymph nodes that theoretically would be the first ‘‘sentinel’’ nodes to receive the lymphatic drainage from the breast harboring the invasive cancer. If these nodes [...]
The following object was noted on gross stool examination. Shown here is the mounted object at 100x, Carmine stain. It measures about 1 mm across and several mm in length, although it does not appear that the whole length is represented here. Identification? (Bonus: list the genus AND species) The Parasite Case of the Week [...]
Parasite Case of the Week 2 can be viewed here: http://pathtalk.org/archives/524 Answer: Tungiasis Congratulations to the 2 readers who wrote in with the correct answer! You both realized that the large size of a foreign appearing organism embedded in skin, combined with the suggestive history, is consistent with Tungiasis. The other commenter gets special bonus [...]
One of our lab techs posed a question about beta-2 transferrin testing on cerebrospinal fluid (CSF). Because beta-2 transferrin is a normal constituent of CSF, but not of plasma or mucosal secretions, it is useful in determining whether a patient’s nose or ear is leaking CSF versus some other fluid. This is important in determining [...]
Bonnie Bassler from Princeton’s Department of Molecular Biology spoke at a recent TED conference on mechanisms of bacterial communication. She explained her group’s discovery that bacteria commnuicate with one another using special “quorum-sensing” molecules which allow them to act in unison, much as the cells in a multicellular organism do. Their discoveries allow for some [...]
HealthDay (4/15, Preidt) reported, “A new imaging technology could help improve the tracking of changes in cancer cells, according to researchers from the Stanford University School of Medicine.” Using “specially designed dye-containing nanoparticles,” the technology allows researchers to “simultaneously measure dozens of features in or on a single cell.” The technology “enhances the detection of [...]
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