It is often important to determine the site of origin of a metastatic carcinoma of unknown primary site, particularly because this may affect the choice of the treatment. Determination of the primary site may take several steps. Clinical features, such as age, sex, and site of metastases may give a first indication.A detailed pathologic examination [...]
Welcome back to the Parasite Case of the Week! I post a new case every Monday, along with the answer to the previous week’s case. Here is our new case for this week: The following were seen under 40x magnification growing on tap water agar, 5 days after inoculation with brain tissue. The patient had [...]
Case 5 can be viewed here. Dr. J and Christopher C. both got this one correct! This is, indeed, Balantidium coli. This organism is the only ciliated parasite to infect humans. At 80 microns or larger in longest dimension, it is also the largest protozoan to infect humans. Shown here is the classic ciliated oval [...]
Check out some nice webinars on digital IHC including one on study results with comparison between glass slide and virtual microscopy. Both are from Dr. Holger Lange at Aperio and can be found at: http://www.aperio.com/IHC/immunohistochemistry-slides.asp. (Scroll to bottom of page).
Most of us accept the party line that there are three basic forms of Creutzfeldt-Jakob disease (CJD): acquired, inherited, and sporadic. The general neurology and neuropathology textbooks do not acknowledge that the very existence of sporadic CJD is controversial. But D.T. Max (picture from nytimes.com), in his book The Family That Couldn’t Sleep: A Medical [...]
Hello, all! It’s my privilege to begin posting on this blog – I’m a first-year anatomic pathology/clinical pathology resident at the Medical College of Wisconsin in Milwaukee and hopefully you’ll find some use out of my contributions to this multi-author blog! I hope to share interesting cases that find their way into my training, blog [...]
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